ancient Iran Revolt of the high satrapies also known as Persia

The empire of the Seleucids, like that of the Achaemenids before them, was shaken by revolts of the satraps. The difficult situation in the west and the grave reverses suffered by the royal house accelerated the weakening of the Macedonian kingdom. The loss of its eastern possessions in the 3rd century bc, however, proved fatal to the Seleucid cause. Diodotus I, a Greek who found himself at the head of the satrapy of Bactria, led a revolt that brought independence about 250 bc; at about the same time, Arsaces led the Scythian Parni into Parthia and defeated Andragoras, establishing an independent native dynasty.

Parthia was the first province to detach itself from the Seleucid empire, just as it had been the first to rise up on the occasion of the accession of Darius the Great. Andragoras, though he did not declare himself king, showed his independence by minting his own coins. At this time Parthia was one of the poorer of the high satrapies, caught between the mountains and the great central desert and without large agricultural resources. This satrapal independence might seem surprising if it were not for the fact that the main route for the silk trade crossed right through Parthia over a distance of more than 100 miles (160 km). The tolls the caravans paid must have produced a sizable income.

The defection of Diodotus I is still easier to understand. Bactria, a vast country of a “thousand cities,” was located at the junction of the routes to China and India, and it was rich in cultivable land. The Greco-Bactrian kingdom founded by Diodotus expanded rapidly, embracing Sogdiana and Aria and extending southward and southeastward.

Being at some distance from the west, Diodotus and his successors gradually adopted the customs and lifestyles of their subjects. The closer these ties were drawn, the stronger became the loyalty of the Bactrians. It is believed that the separation of Diodotus from the Seleucids might, over the long term, have seemed to the Bactrians and Sogdians as the realization of their political destiny, and they might have looked on these satraps as men acting in their interest. For more than a century (230–130 bc) this kingdom held the frontiers and barred the route to the nomads.